Discovery programs move faster when scientific disciplines work together. BioDuro combines medicinal chemistry, synthetic chemistry, peptide science, computational design, and analytical support within a coordinated discovery environment that helps teams make informed decisions earlier.

From hit identification through lead optimization, candidate selection, and preclinical scale-up, scientists work across experimental and computational approaches to rapidly generate compounds, evaluate SAR, and refine discovery strategies.

Chemists collaborate closely with Biology and DMPK teams to assess potency, selectivity, exposure, and developability throughout the discovery process, helping reduce delays and accelerate program progression.

AI-assisted molecular design, virtual screening, and enabling chemistry technologies are incorporated where they can improve efficiency, guide decision-making, and help solve complex chemistry challenges.

Discovery Chemistry Expertise

BioDuro supports a wide range of therapeutic modalities and complex chemistry challenges across modern drug discovery programs.

• Small molecule medicinal chemistry
• Peptides and peptide conjugates
• Antibody-drug conjugate (ADC) linker, payload chemistry and bioconjugation chemistry
• Targeted protein degradation (PROTACs and molecular glues)
• Targeted covalent inhibitors
• Oligonucleotides and nucleosides/tides
• Fragment-based drug discovery
• Natural products, steroids, lipids, and carbohydrates
• Discovery process chemistry and scale-up

Our teams apply these capabilities across hit identification, hit-to-lead, lead optimization, candidate selection, and integrated drug discovery programs.

Seamless Scale-Up Support

Discovery programs often require rapid progression from design to material supply. BioDuro supports synthesis from milligram quantities through multi-hundred-gram scale for pharmacology, DMPK, and toxicology studies, with established pathways for transfer into Process Chemistry and CMC development.

Discovery Without Silos

Chemistry, Biology, and DMPK teams collaborate throughout the discovery process, enabling faster data generation, SAR interpretation, and decision-making from hit identification through candidate selection.

By working in parallel rather than sequentially, teams can rapidly evaluate compounds, refine design strategies, and maintain momentum as programs advance toward development.

Global Project Management

Dedicated project managers provide scientific oversight, streamlined communication, and coordinated support across global teams. With experienced scientific leadership and integrated workflows, programs benefit from clear communication, efficient execution, and continuity throughout the discovery journey.