Services Chemistry Analytical Chemistry
Analytical Chemistry
From purification and rigorous characterization to analysis and structure confirmation, BioDuro’s analytical chemistry team works closely with synthetic chemists to ensure the quality of synthesized compounds and support rapid project turnaround.
Analytical Chemistry That Keeps Discovery Moving
Upon completion of synthesis, compounds undergo purification, characterization, analysis, and structure confirmation by BioDuro’s analytical chemistry team. Our analytical scientists work closely with synthetic chemists and project teams, allowing analytical needs to be addressed quickly as projects progress.
With extensive in-house instrumentation and automation, our experienced analytical team provides reliable, reproducible data with the flexibility and fast turnaround needed for discovery chemistry programs.
Analytical Chemistry Services
Our analytical chemistry team provides a range of services for compound purification, characterization, and analysis.
Method Development
Analytical method development tailored to the compound and specific needs of each project.
Routine Purification
Purification of synthesized compounds using established chromatographic and separation techniques.
Chiral Separation
Analytical and semi-preparative chiral separation for the analysis and purification of enantiomers.
Impurity Analysis
Analysis and characterization of impurities to help assess compound purity and quality.
Thermal Analysis
Thermal characterization using differential scanning calorimetry (DSC).
Particle Characterization
Determination of particle size, shape, and crystallinity.
Analytical Chemistry Capabilities
BioDuro’s analytical laboratories provide a broad range of chromatography, mass spectrometry, spectroscopy, and physicochemical testing capabilities.
Chromatography Separation
- Reverse-phase chromatography by HPLC and UPLC
- Chiral separation
- Analytical and semi-preparative SFC
Mass Spectrometry & Structure Confirmatio
- LC-MS analysis
- GC-MS analysis
- NMR analysis: ¹H, ¹³C, ¹⁹F, and ³¹P nuclei
- 1D and 2D NMR experiments
- Optical rotation determination
Physicochemical & Stability Testing
- Dissolution
- Karl Fischer
- Stability testing
- Physicochemical property testing according to USP and CHP
- Residual solvent determination by GC-FID and ECD
- Particle size, shape, and crystallinity determination
- Thermal analysis by DSC
Analytical Platforms & Instrumentation
BioDuro maintains comprehensive in-house analytical, purification, and chiral separation capabilities for discovery chemistry
Analytical & Purification Instrumentation
More than 100 analytical and purification instruments, including LC-MS, HPLC/UPLC, and GC-MS systems from Agilent, Shimadzu, and Waters, provide broad in-house capacity for compound analysis and purification.
High-Throughput Purification
BioDuro’s purification capacity exceeds 500 samples per day, providing the throughput needed for larger discovery chemistry programs.
Chiral Separation & Purification
BioDuro has 10 chiral separation instruments, including chiral HPLC and SFC systems from Thar, Waters, and Shimadzu.
The in-house chiral column collection includes 20+ analytical and 20+ semi-preparative phases, providing options for a broad range of chiral separations.
Why Teams Work With BioDuro
- Dedicated team of trained analytical chemists
- Close interaction with synthetic chemists and project teams
- Flexible support based on project needs
- Fast turnaround time
- Reproducible, high-quality data
Related Chemistry Resources
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