Synthetic Chemistry

Synthetic chemistry expertise supports complex molecule synthesis, route development, and challenging reaction pathways across modern drug discovery programs. Teams work across a broad range of modalities, including small molecules, peptides, PROTACs, ADCs, oligonucleotides, and other emerging therapeutic approaches.

The focus is on solving synthetic challenges efficiently and generating the compounds needed to keep discovery programs moving forward.

Solving Challenging Chemistry Problems

BioDuro applies synthetic chemistry expertise across complex molecule synthesis, route scouting, and challenging reaction pathways to support medicinal chemistry and discovery programs. Our scientists tackle complex synthetic challenges across diverse molecular classes, including peptides, PROTACs, ADC linkers and payloads, oligonucleotides, carbohydrates, and other specialized compounds requiring innovative synthetic strategies and practical problem solving.

Complex Multi-Step Synthesis

Synthetic chemistry workflows designed to tackle challenging multi-step routes, complex scaffolds, and difficult reaction sequences across modern discovery programs.

  • Complex heterocyclic chemistry
  • Route scouting and optimization

Specialized Chemistry Expertise

Capabilities spanning fluorination, carbohydrates, nucleosides, organometallic chemistry, and other specialized synthetic workflows supporting medicinal chemistry programs.

  • Challenging reaction pathways
  • Advanced synthetic transformations

Discovery Chemistry Collaboration

Synthetic chemistry teams working closely with medicinal chemistry and analytical groups to help advance challenging discovery programs efficiently.

  • Analytical and purification collaboration
  • Integrated discovery chemistry support

Heterocyclic Chemistry

Synthetic workflows supporting the design and synthesis of complex heterocyclic scaffolds commonly used in medicinal chemistry programs.

Fluorination Chemistry

Capabilities supporting selective fluorination strategies designed to improve compound stability, potency, and pharmacokinetic properties.

Carbohydrates & Nucleosides

Experience across carbohydrate chemistry, nucleosides, nucleotides, and other specialized synthetic workflows requiring advanced chemistry expertise.

Route Scouting & Optimization

Synthetic route evaluation and optimization workflows designed to improve scalability, efficiency, and overall synthetic feasibility.