Biophysics
Biophysical characterization services designed to evaluate molecular interactions, binding affinity, and binding kinetics across discovery programs.
BioDuro utilizes Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI) platforms to generate quantitative insights into drug-target interactions. Our scientists support affinity determination, kinetic characterization, target engagement studies, and advanced molecular interaction analysis for small molecules, biologics, and emerging therapeutic modalities.
Quantitative Binding Insights
Generate precise measurements of binding affinity and kinetics to better understand molecular interactions and candidate performance.
- Binding Affinity Determination
- Association & Dissociation Rates
- Kinetic Characterization
Confident Candidate Selection
Evaluate target engagement, interaction profiles, and developability characteristics to support candidate prioritization.
- Target Engagement Analysis
- Binding Stoichiometry Evaluation
- Stability Characterization
Advanced Molecular Characterization
Support complex discovery programs through specialized biophysical workflows and interaction studies.
- Epitope Binning & Mapping
- Fragment Screening Support
- Affinity Maturation Studies
Biacore 8K (SPR)
Surface Plasmon Resonance (SPR) platform supporting real-time analysis of binding affinity, binding kinetics, target engagement, and molecular interactions.
Octet RED384 (BLI)
Bio-Layer Interferometry (BLI) platform enabling rapid characterization of biomolecular interactions, affinity measurements, and kinetic analysis.
Uncle Stability Platform
Integrated thermal and colloidal stability characterization supporting developability assessments, candidate selection, and biologics optimization.
