Resources - BioDuro

A Diet-Induced High Translatable Obesogenic Mouse MASH Model: Validation Across Distinct Therapeutic Mechanisms

This whitepaper presents BioDuro’s HFD-induced MASH mouse model, highlighting its ability to reproduce key disease characteristics and demonstrate consistent responses to clinically relevant therapies.

Biology Chemistry DMPK Drug Product Drug Substance

Peptide

Flyer

Integrated Peptide CRDMO Platform

This flyer introduces BioDuro's fully integrated peptide CRDMO platform, bringing these capabilities together to support peptide programs from early discovery through development and manufacturing.

DMPK

Whitepaper

Influence of 1-Aminobenzotriazole on Metabolism of Antipyrine: A Cross-Species DMPK Study

Explore how CYP inhibition affects antipyrine metabolism in cats and guinea pigs, revealing species-specific differences in metabolic pathways and drug exposure. This whitepaper offers practical insights for cross-species DMPK interpretation and animal model selection.

Uplc–hrms identification of t dm1 payload containing catabolites in human liver lysosomes

DMPK

Antibody-Drug Conjugate

Case study

UPLC–HRMS Identification of T-DM1 Payload-Containing Catabolites in Human Liver Lysosomes

This case study presents a systematic profiling of T-DM1 payload containing catabolites generated in human liver lysosomes, offering critical insights into the ADC's processing pathways that directly inform efficacy, safety, and risk assessment.

Drug Product Drug Substance

Peptide

Flyer

Peptide CMC Capability

This flyer introduces BioDuro's cross‑functional peptide CMC solution, designed to tackle the unique challenges of peptide development, from early‑phase design through IND readiness and commercial manufacturing.

Biology Chemistry DMPK

Peptide

Flyer

GLP-1 Platform

Highlights BioDuro's advanced LC-HRMS workflow for unbiased peptide metabolite profiling, supporting DMPK strategies and candidate selection.

Antibody oligonucleotide conjugate synthesis for controlled oars

Chemistry

Antibody-Drug Conjugate

Case study

Antibody-Oligonucleotide Conjugate – Synthesis for Controlled OARs

This case study highlights a successful AOC development program that overcame the inherent complexity of these large, charged, and structure sensitive molecules— delivering well defined conjugates with controlled oligonucleotide to antibody ratio and high purity.

Biology

Flyer

Discovery Biology

Highlights BioDuro's integrated discovery biology capabilities, delivering customized assays, advanced screening, and actionable insights to accelerate drug discovery.

Venetoclax resistant aml cell models as a platform for overcoming bcl2 inhibitor resistance

Biology

Whitepaper

Venetoclax-Resistant AML Cell Models as a Platform for Overcoming BCL2 Inhibitor Resistance

This whitepaper introduces a validated panel of venetoclax-resistant AML cell models—engineered to mirror the resistance seen in the clinic.

DMPK

Flyer

DMPK Services

Discover BioDuro's integrated DMPK services that accelerate candidate selection, reduce risk, and support IND-enabling programs.

Chemistry

Flyer

Discovery Chemistry Engine

Accelerate drug discovery with BioDuro's integrated chemistry expertise. Our teams support hit identification, lead optimization, candidate selection, and scale-up across small molecules, peptides, ADCs, PROTACs, and other emerging modalities.

Chemistry Drug Substance

IND Enabling

Case study

Bridging Discovery and Process Development: A streamlined 18-month path from hit to IND for a CNS project

See how BioDuro advanced a CNS program from hit to IND in just 18 months through integrated discovery and process development.