Biochemistry

BioDuro’s biochemical assays measure molecular interactions between drug candidates and biological targets, including enzymes, receptors, and other proteins. These data help researchers evaluate binding affinity, enzyme activity, potency, selectivity, and mechanism of action to support hit identification, lead optimization, and candidate selection.

Biochemical assays provide critical insights into compound activity and target engagement early in the discovery process. They help researchers:

• Identify promising drug candidates through quantitative activity and binding data
• Evaluate potency and selectivity against biological targets
• Support mechanism-of-action studies
• Generate data to guide hit-to-lead and lead optimization efforts

Biochemical assays evaluate molecular interactions, such as enzyme activity, target inhibition, and receptor binding, in controlled assay systems.

Cell-based assays measure biological responses within living cells, providing additional insight into cellular activity, pathway modulation, and compound effects.

Together, these approaches provide a comprehensive understanding of compound performance.

Yes. BioDuro develops and optimizes customized biochemical assays based on the target biology, therapeutic area, and program objectives. Our scientists work closely with clients to design robust assay strategies that deliver reliable and reproducible data.

BioDuro supports a broad range of biochemical assay formats, including:

• Enzymatic assays
• Binding assays
• Kinase assays
• GPCR binding assays
• Epigenetic target assays
• Mechanism-of-action studies
• Custom assay development