CNS & Pain
BioDuro offers a broad portfolio of validated in vivo disease models supporting efficacy studies across neurodegenerative, neurological, inflammatory, and pain-related disorders.
Our team works closely with clients to select the most appropriate models based on therapeutic targets, disease biology, and study objectives.
Neurodegenerative Disease Models
Evaluate therapies targeting progressive neurodegenerative disorders.
Parkinson’s disease
- MPTP acute model
- MPTP chronic model
- 6-OHDA model
Alzheimer’s disease
- 5xFAD transgenic mouse model
Amyotrophic Lateral Sclerosis (ALS)
- SOD1-G93A mouse model
Neurological Disease Models
Established models for studying a broad range of neurological disorders.
Stroke
- Transient middle cerebral artery occlusion (tMCAO) model
Epilepsy
- PTZ-induced epilepsy model
Perioperative Neurocognitive Disorder (PND)
Sleep Disorders
- Sleep deprivation model
- Caffeine-induced sleep disturbance model
Neuroinflammation & Related Models
Models used to investigate neuroinflammation and other CNS disorders.
Neuroinflammation
- LPS-induced neuroinflammation
Hepatic Encephalopathy
- Thioacetamide-induced hepatic encephalopathy
NMDA Receptor Dysfunction
- MK801 model
Respiratory Depression
- Morphine-induced respiratory depression
