Fragment-Based Drug Discovery (FBDD)
Find Your Next Hit with BioDuro’s Fragment Screening Platform
Leverage a differentiated fragment library featuring proprietary, internally synthesized scaffolds and high-throughput SPR screening to identify novel starting points for drug discovery.
High-Quality Fragment Library
A differentiated fragment collection designed to improve novelty, diversity, and screening efficiency across modern discovery campaigns.
- ~2,300 total fragments
- ~1,300 novelty fragments
- Natural product-inspired scaffolds
SPR Screening & Affinity Characterization
Integrated SPR workflows supporting fragment screening, affinity evaluation, and kinetics characterization across early discovery programs.
- Biacore 8K screening platform
- Kd characterization from nM–mM
- Affinity and kinetics analysis
Discovery-Oriented Fragment Design
Fragment selection strategies designed to improve chemical tractability, scaffold diversity, and downstream medicinal chemistry progression.
- Relaxed Ro3 fragment strategy
- Structural alert filtering workflows
- Follow-up chemistry optimization support
SPR Screening Platform
Biacore 8K SPR workflows supporting high-throughput fragment screening, affinity characterization, and kinetics analysis.
- Kd range from nM–mM
- Quantitative binding characterization
High-Throughput Screening Workflows
Fragment screening workflows supporting both 96- and 384-well plate formats for efficient discovery execution.
- Parallel screening setup
- Multi-channel screening support
Affinity & Kinetics Analysis
Biophysical workflows designed to evaluate binding affinity, kinetics behavior, and fragment interaction profiles.
- kon/koff characterization
- Binding stoichiometry analysis
Fragment Library Platform
Differentiated fragment collection designed to improve novelty, scaffold diversity, and medicinal chemistry tractability.
- ~2,300 fragment library
- Internally synthesized novelty fragments
