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Metabolic & Cardiovascular

Over 50 validated in vivo models supporting metabolic and cardiovascular disease research across diabetes, obesity, MAFLD/MASH, chronic kidney disease, heart failure, hyperlipidemia, hypertension, thrombosis, and related disorders.

BioDuro provides integrated in vivo pharmacology services that help researchers evaluate therapeutic candidates, investigate disease biology, and generate data supporting metabolic and cardiovascular drug discovery programs.

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Metabolic & Cardiovascular Capabilities

BioDuro offers a diverse portfolio of validated disease models and in vivo pharmacology capabilities supporting metabolic, cardiovascular, and cardiorenal research.

Metabolic Disorders

Evaluate therapeutic candidates in validated models of metabolic disease and metabolic dysfunction.

  • Type 1 Diabetes
  • Type 2 Diabetes
  • Obesity
  • MAFLD/MASH

Cardiovascular Diseases

Support cardiovascular research through established models of cardiac and vascular disease.

  • Heart Failure
  • Hypertension
  • Thrombosis
  • Myocardial Infarction

Cardiorenal Disease Models

Investigate the complex relationship between metabolic, renal, and cardiovascular disorders using validated disease models and pharmacology platforms.

  • Chronic Kidney Disease (CKD)
  • Renal Injury Models
  • Metabolic Dysfunction Studies
  • In Vivo Pharmacology Assessments

Supporting Metabolic & Cardiovascular Research

BioDuro’s in vivo pharmacology capabilities help researchers evaluate therapeutic candidates, investigate disease biology, and generate data that support metabolic and cardiovascular drug discovery programs.

Therapeutic Efficacy Evaluation

Assess treatment responses and biological outcomes using validated disease models across metabolic and cardiovascular disorders.

Disease Mechanism Investigation

Study disease progression and underlying biological pathways to better understand therapeutic impact and target biology.

Metabolic Phenotyping

Characterize metabolic function through established pharmacology assessments, including glucose metabolism, energy expenditure, and body composition analysis.

Candidate Selection

Generate data that support informed decision-making and the advancement of promising therapeutic candidates.

Related Resources

Explore scientific resources highlighting BioDuro’s expertise in metabolic disease, cardiovascular research, translational biology, and integrated drug discovery. These examples demonstrate how advanced biology platforms support target validation, efficacy evaluation, biomarker analysis, and the development of novel therapeutics for complex metabolic and cardiovascular disorders.

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March 30, 2026 Article Chemistry

Sustaining Client Trust through a Comprehensive Discovery Chemistry Platform | A Conversation with Dr. Li Feng

Building lasting trust with our clients is at the heart of what we do. In 2025, Daewoong Pharmaceutical recognized BioDuro as Best CRO in 2025, a mark of the tr...
Peptide del screening cover image
February 8, 2026 Article Chemistry

BioDuro Advances DNA-Encoded Peptide Libraries: 108-Channel Automation Enables 10-mer+ DNA-Encoded Macrocycles for High-Throughput Drug Discovery

DNA-encoded library (DEL) technology has emerged as a powerful alternative to traditional phage and mRNA display methods for high-throughput peptide discovery. ...
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July 14, 2025 Article Biology

In Vitro Evaluation for STAT6 Degraders, Using Kymera’s Patented Molecule as an Example

To uncover the story behind one of the most promising frontiers in immunology and drug discovery, we sat down with Lin Teng, PhD, head of Biology Department at ...
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September 30, 2025 Article Chemistry

Fragment-Based Drug Discovery: A Unified Workflow for Efficient Lead Generation

This article, with insights from Babu Boga, Vice President of Medicinal Chemistry and Xiang Li, President of the Chemical Division, BioDuro, was originally publ...
Optimization of High-Throughput 96-Well Hepatocyte Stability Assay
Case study DMPK

Optimization of High-Throughput 96-Well Hepatocyte Stability Assay Setup and Cross-Species Validation

iscover how BioDuro's optimized high-throughput hepatocyte stability assay accelerates early drug discovery while maintaining data reliability....
DMPK TN12
Case study DMPK

Multi-Species Hepatocyte Metabolism of GLP-1(28–36)amide by UPLC-HRMS for Comprehensive Metabolite Profiling

Demonstrates BioDuro's peptide DMPK expertise through integrated LC-HRMS metabolite profiling, enabling confident identification and optimization of peptid...

Related Biology Services

Metabolic and cardiovascular studies are often integrated with complementary biology services to investigate disease mechanisms, evaluate therapeutic candidates, and generate translational insights across discovery programs.

Peptide Biology CNS & Pain Oncology Immunology & Inflammation Cellular Disease Models Cell Biology Cell Line Engineering Biophysics Biochemistry Target Validation