Services CMC QA & EHS
QA & EHS
Drive your program from Hit-to-Lead to PCC with a team of 1,000+ chemists. We combine massive synthetic capacity with US-led strategic problem solving.
Accelerate your Make-Test-Decide cycles.
Scale is meaningless without speed. We convert our synthetic capacity into discovery velocity, tightening the loop between design and execution. This allows you to iterate faster and reach decision-enabling data without the management overhead of traditional outsourcing.
Unmatched Throughput.
From milligram library synthesis to kilogram scale-up. Our sheer capacity allows for parallel exploration of diverse chemical space, shortening your “Make” cycle significantly.
- Responsive Project Management
- Broad Therapeutic Expertise
Expert Design & CADD
We don’t just execute ticket orders. Our senior leaders (20% PhDs) actively contribute to SAR analysis and scaffold hopping strategies using AI-driven CADD tools.
- Multi-Parameter Analysis (MPA)
- Patent Creation Strategies
US-Standard IP Protection.
Your IP is secure. With US-managed data systems and strict firewall protocols, you get the economic advantage of global execution with the security of a Western partner.
- Deep Integration with Biology Teams
- Zero-Compromise Data Security
Support across every stage of discovery.
BioDuro offers a full suite of medicinal chemistry services, including:
Hit Identification
The process of finding compounds that interact with a biological target, such as a protein.
Hit to Lead
Through evaluation and modification of “hit” compounds to enhance their potential.
Lead Optimization
Further refinement of a compound’s properties to develop a drug candidate.
Patent filing support
Guidance through the patent filing process for new drug compounds.
Key instruments
Complex synthesis requires more than just standard protocols. See how our chemists navigate multi-step challenges to deliver high-purity compounds where standard solid-phase methods often fail.
PTI Symphony X
- 0.1-0.2 mmol
- N2 protection
- 24 channels
CEM MultiPep2
- 0.1-0.2 mmol
- N2 protection
- 24 channels
Tetras Volo
- 0.1-0.2 mmol
- N2 protection
- 24 channels
DL-PSI-286
- 0.1-0.2 mmol
- N2 protection
- 24 channels
Common Questions
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Medicinal chemistry involves designing and optimizing drug molecules to ensure that compounds are safe and effective before advancing in the development process.
Medicinal chemistry involves designing and optimizing drug molecules to ensure that compounds are safe and effective before advancing in the development process.
Medicinal chemistry involves designing and optimizing drug molecules to ensure that compounds are safe and effective before advancing in the development process.
Medicinal chemistry involves designing and optimizing drug molecules to ensure that compounds are safe and effective before advancing in the development process.
Download our full Medicinal Chemistry Fact Sheet
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Parallel Synthesis Services
BioDuro offers synthesis and purification services to deliver both small and large libraries, with expertise to overcome discovery stage challenges and capacity for process scale-up of drug substance.
Small libraries
- 10 – 50mg of each compound
- Purity – ≥90% (95% if desired) by HPLC/LC-MS for all compounds
- 1H-NMR for 5- 10% (or more, if required) of the compounds
Large libraries
- 10mg of each compound
- Purity – ≥85% by (90% if desired) HPLC/LC-MS for all compounds
- In general 1H-NMR for 5 – 10% of the compounds
Success in Action
Complex synthesis requires more than just standard protocols. See how our chemists navigate multi-step challenges to deliver high-purity compounds where standard solid-phase methods often fail.
42-Step Liquid-Phase Synthesis: Achieving 99% Purity
Challenge: Synthesizing the reference peptide MK-0616. Solution: Our team deployed a specialized liquid-phase strategy to overcome aggregation issues, delivering the target at >99% purity.
42-Step Liquid-Phase Synthesis: Achieving 99% Purity
Challenge: Synthesizing the reference peptide MK-0616. Solution: Our team deployed a specialized liquid-phase strategy to overcome aggregation issues, delivering the target at >99% purity.
Related Resources
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Partnership solutions
Flexible ways to engage our chemistry teams
Strategic leadership from target to candidate.
Let our project leaders drive the full DMTA cycle. We coordinate chemistry, biology, and DMPK to accelerate your path from Hit to PCC.
Dedicated scientists working exclusively on your systems.
Extend your internal capacity with a dedicated team of BioDuro-Sundia chemists working exclusively on your projects and systems.
A complete safety & tox package for regulatory submission.
streamlined transition from PCC to IND. We combine GLP-tox batch synthesis with safety assessment to get you regulatory-ready in record time.
Integrated Chemistry Services
Accelerate your discovery cycles by leveraging our full spectrum of chemistry capabilities. Whether you need parallel synthesis for library generation or computational insights for scaffold hopping, these integrated services act as force multipliers for your medicinal chemistry program.
Ready to accelerate your program?
Whether you need a strategic consultation, technical data, or have a general inquiry, our team is ready.
Request a Consultation
Speak directly with a scientific project leader about your challenges.
General Inquiries
For careers, media, or general questions not related to active projects.