Integrated Biology
In vitro biology and in vivo pharmacology expertise spanning target validation, assay development, lead optimization, and translational discovery.
Working alongside Chemistry and DMPK, BioDuro’s biology scientists help connect screening, pharmacology, and translational data across discovery programs.
Advancing Discovery Biology Across Diverse Modalities
BioDuro’s biology teams work across oncology, immunology, immuno-oncology, metabolic disease, and general safety evaluation, supporting discovery programs from early screening through candidate optimization.
Capabilities span biochemical assays, cellular assays, phenotypic screening, target engagement, and translational biology workflows across both in vitro and in vivo systems. Our teams also support emerging therapeutic modalities including peptides, ADCs, PROTACs, molecular glues, RNA therapeutics, and antibody-based programs.
Core Biology Expertise
Biochemical & Target-Based Assays
Biochemical and mechanistic assays supporting kinases, GPCRs, enzymes, ion channels, nuclear receptors, and additional target classes across discovery programs.
Cellular & Phenotypic Biology
Target-based, phenotypic, and protein marker-based cellular assays designed to evaluate compound activity, signaling, viability, and functional response across diverse disease areas.
Translational & In Vivo Pharmacology
In vivo pharmacology models and translational workflows supporting efficacy evaluation, lead optimization, and data-driven progression across discovery programs.
Specialized Discovery Platforms
Capabilities include CRISPR-Cas gene editing, stable cell line generation, recombinant protein production, fragment-based drug discovery, biophysics platforms, and PROTAC biology evaluation.
Technology & Discovery Platforms
Advanced biology technologies supporting target engagement, screening, and translational characterization across modern drug discovery workflows.
- High-content imaging
- Flow cytometrySPR/BLI biophysics
- TR-FRETN
- NanoBRET
- AlphaLISA
- HiBiT
- Radioisotope assays
Built for Modern Discovery Programs
From target validation through lead optimization, BioDuro’s biology teams help discovery groups generate actionable biological data with the speed, scientific depth, and cross-functional alignment required for modern therapeutic development.
Services overview
