High Translatable DIO Rodent Model: Accelerating Weight Loss Drug Discovery

Friday, November 14, 2025 | 8am PDT/11am EDT

Obesity remains a critical global health threat, affecting over one billion people worldwide and exacerbating risks for type 2 diabetes, cardiovascular diseases, and fatty liver disease. The pharmaceutical landscape is witnessing rapid transformation through novel oral GLP-1 agents, long-acting injectables, and multi-target therapies that are redefining treatment possibilities.

At the preclinical stage, BioDuro’s Diet-Induced Obesity (DIO) rodent models, enhanced with high-resolution phenotyping tools, create a crucial translational bridge to accelerate weight loss drug development.

What you will learn

  • Review emerging obesity targets and clinical development progress.
  • Compare and select optimal rodent models for obesity research.
  • Design effective efficacy studies for weight loss compounds.
  • Enhance translation between preclinical and clinical study outcomes.

Speakers

John Liu, Ph.D.
John Liu, Ph.D. Head of Pharmacology, BioDuro

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