High Translatable DIO Rodent Model: Accelerating Weight Loss Drug Discovery
Friday, November 14, 2025 | 8am PDT/11am EDTObesity remains a critical global health threat, affecting over one billion people worldwide and exacerbating risks for type 2 diabetes, cardiovascular diseases, and fatty liver disease. The pharmaceutical landscape is witnessing rapid transformation through novel oral GLP-1 agents, long-acting injectables, and multi-target therapies that are redefining treatment possibilities.
At the preclinical stage, BioDuro’s Diet-Induced Obesity (DIO) rodent models, enhanced with high-resolution phenotyping tools, create a crucial translational bridge to accelerate weight loss drug development.
What you will learn
- Review emerging obesity targets and clinical development progress.
- Compare and select optimal rodent models for obesity research.
- Design effective efficacy studies for weight loss compounds.
- Enhance translation between preclinical and clinical study outcomes.
Speakers
John Liu, Ph.D.
Head of Pharmacology, BioDuro