Exploring Peptide In-Vitro ADME Properties: From Natural Peptides to Synthetic Analogues
Did you miss the live webinar on June 13, 2025, Exploring Peptide In-Vitro ADME Properties: From Natural Peptides to Synthetic Analogues? Watch it on-demand now!The design of synthetic peptide analogues offers potential to overcome several inherent limitations of natural peptides, including rapid degradation, poor permeability and adverse effects.
This webinar will discuss key absorption, distribution, metabolism and excretion (ADME) characteristics in peptide drug development, showcasing in-vitro data from representative examples across different peptide classes, including natural peptides, hormones, cyclic peptides, GLP-1 analogues and synthetic D-amino acid peptides.
What you will learn
- Evaluation of peptide stability in biological matrices (plasma, liver, intestine, kidney) and resistance to proteases
- Mechanisms of protease resistance and strategies for improving metabolic stability
- Assessment of in-vitro permeability and factors affecting absorption
Speakers
Haoqing Chen, Ph.D.
Lead of ADME, BioDuro