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Rapid Formulation Development of Amorphous Solid Dispersions by Combined In-Silico Modeling, High-Throughput Screening and In-Vivo PK Study
Discover how BioDuro's innovative formulation platform accelerates the development of Amorphous Solid Dispersions (ASDs) to enhance drug solubility and bioavailability—using minimal API and time. This case study showcases a streamlined, integrated approach combining in-silico modeling, high-throughput screening, and in-vivo studies to rapidly identify optimal formulations.
Key Highlights
- Efficient API Use: Only 100–200 mg required for full evaluation and in-vivo PK studies
- Rapid Turnaround: In-vitro and in-vivo results delivered within 8 weeks
- Enhanced Bioavailability: Achieved up to a 12-fold improvement in preclinical models
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