Case study
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July 30, 2025
Validation of BSEP, MRP1, MRP2, MRP3, and MRP4 Substrate Assays using Human Membrane Vesicles
Gain critical insights into drug safety and transporter interactions with BioDuro's validated vesicle-based assays for BSEP, MRP1, MRP2, MRP3, and MRP4. This robust in vitro platform helps identify compounds prone to drug-induced liver injury (DILI) and drug-drug interactions (DDI) early in development—enabling smarter candidate selection and reducing late-stage attrition.
Key Highlights
- Proactive De-risking: Identify transporter-mediated liabilities before they impact clinical outcomes.
- Rigorous Validation: Meet strict acceptance criteria with reliable, reproducible results.
- Accelerated Decision-Making: Streamline compound advancement with high-confidence data.
Download the full case study to discover how our platform enables safer compound selection and accelerates development toward IND.