Optimization of High-Throughput 96-Well Hepatocyte Stability Assay Setup and Cross-Species Validation
Discover how BioDuro's optimized high-throughput hepatocyte stability assay accelerates early drug discovery while maintaining data reliability. This case study demonstrates a validated 96-well platform that delivers consistent metabolic clearance results across multiple species—enabling more efficient screening and data-driven decisions during early discovery.
Key Highlights
- Enhanced Throughput: Transition from 24-well to 96-well format significantly increases screening capacity without compromising data integrity.
- Cross-Species Validation: Reliable performance confirmed across human, cynomolgus, beagle, rat, and mouse hepatocytes.
- Streamlined Workflow: Supports parallel processing of multiple compounds, accelerating project timelines and resource efficiency.
- Operational Guidance: Clear volume-based recommendations ensure robust and reproducible results in routine screening.
This optimized assay provides a scientifically sound, high-throughput solution for metabolic stability testing, empowering faster and more confident decision-making in early discovery.
Download the full case study to advance your screening capabilities with a proven, efficiency-driven approach.