Peptide Drug Discovery Overview
At BioDuro-Sundia, we leverage decades of experience and expertise in
peptide chemistry to deliver high-quality peptides, from milligram to gram scales. Our state-of-the-art facilities, including a dedicated 1,500 m² peptide synthesis center in Beijing, are equipped with top-class instruments and supported by a team of 100+ experienced chemists.
Click here to download the PDF version of our peptide synthesis services flyer. AI Empowered Peptide Discovery
Empowered by Atombeat’s Hermite® software and RiDYMO® platform, enhanced by Reinforced Dynamics, Uni-Dock, Uni-FEP, and Uni-QSAR, we can explore over one trillion peptide compounds built from more than 1,000 natural and non-natural amino acids.
AI assisted virtual screening (by Atombeat): Rapid filtering based on key developability traits such as membrane permeability, advancing only the most promising compounds
High-throughput synthesis: Parallel production of hundreds of peptides within one week
Without purification steps: High-purity peptides delivered directly
Seamless to biology: Direct transition from in silico design to biology assays for rapid validation
Discovery Peptide Chemistry
Our broad peptide synthesis capabilities support a variety of peptide catalogs including linear, cyclic, modified, and conjugated peptides.
Linear Peptide
Expertise: Linear peptide with up to 70 amino acids, including hindered unnatural amino acids
Fast Delivery: a typical turnaround time of 5 days for peptide with 40 amino acids
Versatile Salt Forms Available: including TFA, acetate, and HCl
Cyclic/Macrocyclic Peptide
Lactam cyclic peptide
Thioether-cyclized peptide
Stapled peptide
Multiple disulfide bonds
Click peptide
Cyclic lipopeptide
Modified Peptide
Dye and fluorescent labels
Glycosylation
Phosphorylation
N-terminal modification
C-Terminal modification
Special Peptide
Hydrophobic sequence
Cell-penetrating peptide
PEGylated peptide
Lipidation
Peptidomimetics
Peptoid
Depsipeptide
Peptide Conjugate
Metal chelating conjugate (RDC)
Peptide drug conjugate (PDC)
Typical Peptide Delivery Cycle Time (<100 mg)
Automatic Peptide Synthesizers
Case Studies in Macrocyclic Peptide Synthesis
Cutting-edge Kilogram-scale Peptide Scale-up Capabilities
Solid-phase Peptide Synthesis (SPPS) up to 800 mmol, enabling efficient production of linear peptides, cyclic peptides, and various peptide drug conjugates (PDC)
Liquid-phase Peptide Synthesis (LPPS) capabilities also available to support seamless scale-up and ensure efficient project delivery
Other In-House Capabilities to Empower Your Innovation
Our
Discovery Biology department provides a comprehensive suite of capabilities, including cell-free assays, cellular assays, and in vivo efficacy models, ensuring accurate and reliable data to support research.
Our
DMPK department offers comprehensive services, rigorously screening candidates to optimize drug-like properties and accelerate development timelines.
Our
Formulation department leverages expertise in enteric coating and permeation enhancement technologies to help enhance the bioavailability and efficacy of oral peptide delivery.
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