Optimizing Protocols to Seamlessly Transfer Med. Chem. Synthesis to Process Development

The transition from drug discovery to process development presents significant challenges. Developing scalable synthetic routes, sourcing high-quality reagents in large quantities, ensuring efficient technology transfer, and aligning tight project timelines across departments to meet customer needs can all create obstacles. These hurdles can delay the delivery of toxicology and clinical batches of the API, leading to costly setbacks for drug developers. However, when medicinal and process chemistry teams collaborate toward a shared goal of accelerating early-phase development for IND filing, these challenges can be systematically addressed.

In this webinar, our Head of Medicinal Chemistry and Head of Process Chemistry will spotlight three representative case studies that illustrate how our collaborative approach overcomes key challenges and accelerate timeline from discovery to early clinical milestones.

• Case Study 1: Optimizing synthetic routes and processes to rapidly deliver tox batches of APIs

• Case Study 2: Tackling complex synthesis and scale-up challenges with tailored chemical strategies where conventional approaches fell short

• Case Study 3: Showcasing the synergy between medicinal and process chemistry teams that enabled a seamless transition to development and ultimately to successful IND filings.
  

Topics Covered:

Watch On-Demand

Speakers:

Xiang Li

President of the Chemistry Division

BioDuro

Qixuan Lu

Vice President of Process Chemistry

BioDuro