Oncology

Combining classic and cutting-edge in vitro and in vivo research to support drug discovery efforts for cancer treatment.

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Oncology

Combining classic and cutting-edge in vitro and in vivo research to support drug discovery efforts for cancer treatment.

Overview

Our Oncology department is committed to providing high quality preclinical services to support anti-cancer drug discovery in 2D and 3D cellular models and xenograft mice tumor models. With an experienced scientific team and a panel of validated assays and cancer animal models, we assist pharmaceutical companies and academic researchers in the discovery of novel drug targets and evaluation of anti-cancer small molecules or biologics.

BioDuro Advantage

Experienced scientific team with a strong background in cancer biology

Combination of classic and cutting-edge cancer research models and platforms

Dedicated and collaborative project management

High quality, time and cost-efficient services to clients

Advanced laboratory equipment and a state of the art AAALAC accredited vivarium

Integrated drug discovery solutions with Medicinal Chemistry, DMPK, and Formulation Development

Core Competencies

Cancer animal models

More than 450 available cancer cell lines and more than 270 CDX models

More than 90 PDX models

17 available syngeneic mouse tumor models (useful for immuno-oncology models)

More than 40 Luciferase labeled cancer cell lines and CDX models

More than 12 drug resistant cell lines and xenograft models

Live phase tumor imaging for luciferase-labeled CDX

Subcutaneous and orthotopic tumor models

Experimental metastatic tumor models

Systematic leukemia, lymphoma and multiple myeloma models

PK/PD, general early toxicity studies

Histology and IHC analysis

Downstream signal and biomarker analysis (RT-PCR, western blot, FACS)

Oncology

PDX CDX Orthotopic Models Syngeneic Models Humanized Mouse Models CAR-T and CAR-NK Mouse Models ELISA Assays In Vitro Assays

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