Envision Multilabel Plate Reader (PerkinElmer) |
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- For general drug discovery research
- Detection: AlphaScreen, fluorescence intensity, fluorescence Polorization, time-resolved fluorescence (TRF), luminescence and absorbance
- Applications
- Cellular reporter gene assays: single and dual luciferase; GFP, beta lactamase
- Cellular GPCR assays: HTRF cAMP, AlphaLisa
- Biochemical and cellular enzyme assays: LANCE, DELFIA, HTRF and kinetic studies
- Genotyping: SNP
- Quantification assays: UV/Vis spec.; ELISA
- Manufacturer's website
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EnSpire™ Multilabel Plate Reader (PerkinElmer) |
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- For general drug discovery research
- Detection: Optical biosensor label-free, fluorescence intensity, absorbance, luminescence and AlphaScreen
- Applications
- AlphaScreen
- Luciferase reporter gene assay
- DNA, RNA and protein quantification
- Manufacturer's website
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FLIPR Tetra (Molecular Device) |
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- For GPCR and ion channel research
- 96-w and 384-w heads
- Measure fluorescence and luminescence
- Fast kinetic cellular assays
- Calcium flux (FLIPR and aequorin assay)
- Membrane potential
- Manufacturer's website
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Flexstation 3 (Molecular Device) |
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- For general drug discovery research
- Scanning fluorometer and integrated fluid transfer workstation
- Calcium and potassium ion channel flux
- GPCR Gq-coupled calcium flux
- Membrane potential
- Fatty acid uptake
- cGMP and cAMP assays
- Manufacturer's website
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SECTOR Imager 6000 (MSD) |
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- For general research
- Quantification of cytokines, chemokines, phosphoproteins, biomarkers and metabolites
- Applications:
- Measuring cytokine secretion
- Screening for substrate phosphorylation or other modifications by activation of enzyme, kinase or GPCR
- Manufacturer's website
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TopCount NXT Gamma Counter (Packard) |
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- For Enzyme, GPCR and ion channel research
- A liquid scintillation counter for radiometric assays
- Competitive binding assays
- Filtration (filter binding) assays
- Enzyme assays
- RIA assays
- Manufacturer's website
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Accuri C6 Flowcytomer |
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- Measure physical (shape and size) and chemical (surface and intracellular protein and DNA) properties of cells
- Applications:
- Determining surface receptor and intracellular protein/cytokine expression levels
- Identifying and quantifying distinct cell population
- Measuring calcium flux
- Immunophenotyping
- Determining nucleic acid content
- Measuring enzyme activities
- Cell apoptosis studies
- Manufacturer's website
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SPR-2 (sierra sensors) |
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- For label-free detection of surface plasmon resonance
- Measure the molecular interactions of small molecule/protein and protein/protein
- Applications:
- Determining kinetic rates and affinity constants of binding events
- Manufacturer's website
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